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All products discussed on this site are Research Use Only (RUO) compounds intended strictly for laboratory research. Nothing here is medical advice, and these products are not for human or veterinary use.

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Tirzepatide: Research Profile, Dosages & Supplier Prices

GLP-1/GIP agonist · Lyophilized vial (research); pre-filled pens (pharmaceutical) · Also known as: Mounjaro (brand), Zepbound (brand), LY3298176

Tirzepatide is a glp-1/gip agonist compound with a molecular weight of 4813.5 g/mol and a research half-life of approximately 5 days (~117 hours) in published human pharmacokinetic data. Tirzepatide is a dual GIP and GLP-1 receptor agonist - a single 39-amino-acid peptide engineered to activate both incretin receptors. It is the active ingredient in Mounjaro and Zepbound. The dual-agonist design produced the largest weight reduction effects published in metabolic clinical trials at the time (the SURMOUNT and SURPASS programs).

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

Sequence39-amino-acid peptide with Aib substitutions and C20 fatty diacid modification
FormulaC225H348N48O68
Mol. weight4813.5 g/mol
Half-lifeApproximately 5 days (~117 hours) in published human pharmacokinetic data
Forms soldLyophilized vial (research); pre-filled pens (pharmaceutical)

What is Tirzepatide?

Research interest covers dual incretin receptor pharmacology, comparative metabolic signaling versus selective GLP-1 agonists, and weight regulation pathways.

Tirzepatide is a complex, expensive synthesis. In the RUO market it carries the same counterfeiting risks as semaglutide - verify third-party mass spec confirmation of the 4813.5 g/mol molecular weight on every batch COA.

Mechanism of Action (Research Context)

Dual agonist at GIP and GLP-1 receptors, with engineered imbalance favoring GIP receptor activity. The C20 fatty diacid chain enables albumin binding and a ~5 day half-life.

Research Areas

Dual incretin pharmacologyMetabolic researchWeight regulation pathwaysComparative GLP-1 vs GIP/GLP-1 signaling

Tirzepatide Dosages in Research

5mg10mg15mg

Published clinical research titrated once-weekly doses from 2.5mg to 15mg in human trials. Research vials commonly sold at 5mg, 10mg, and 15mg. Laboratory research use only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C. Reconstituted: 2-8C, use within 30 days. Do not freeze after reconstitution.

Tirzepatide Supplier Price Comparison

No tracked suppliers stock Tirzepatide yet — inventory syncs run continuously. Check our supplier reviews.

Tirzepatide FAQ

Semaglutide activates only the GLP-1 receptor; tirzepatide activates both GIP and GLP-1 receptors. Published head-to-head research (SURPASS-2) showed greater weight and glycemic effects with tirzepatide in human trials.
HPLC purity of 98%+, mass spectrometry confirming 4813.5 g/mol, and third-party lab attribution. Given synthesis complexity, unusually cheap tirzepatide is a major red flag.
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