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All products discussed on this site are Research Use Only (RUO) compounds intended strictly for laboratory research. Nothing here is medical advice, and these products are not for human or veterinary use.

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SS-31: Research Profile, Dosages & Supplier Prices

Mitochondrial research · Lyophilized powder · Also known as: Elamipretide, Bendavia, MTP-131

SS-31 is a mitochondrial research compound with a molecular weight of 639.8 g/mol and a research half-life of ~2-4 hours. SS-31 (elamipretide) is a synthetic tetrapeptide from the Szeto-Schiller series, engineered to selectively target the inner mitochondrial membrane. Its alternating aromatic-cationic motif lets it cross cell membranes freely and concentrate in mitochondria, where it binds cardiolipin - the signature phospholipid of the inner membrane that anchors the electron transport chain complexes.

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

SequenceD-Arg-2',6'-dimethylTyr-Lys-Phe-NH2
FormulaC32H49N9O5
Mol. weight639.8 g/mol
Half-life~2-4 hours
Forms soldLyophilized powder

What is SS-31?

By stabilizing cardiolipin, SS-31 improves cristae architecture and electron transport efficiency while reducing electron leak and reactive oxygen species generation at the source. It has been through numerous clinical trials (as elamipretide/Bendavia) for mitochondrial myopathies, heart failure, and Barth syndrome, giving it one of the deepest clinical datasets of any research peptide. Preclinical research covers ischemia-reperfusion injury, neurodegeneration, muscle aging and kidney disease models.

Mechanism of Action (Research Context)

Selectively partitions into the inner mitochondrial membrane and binds cardiolipin, stabilizing cristae curvature and respiratory supercomplex organization. Reduces electron leak and mitochondrial ROS production, improves ATP synthesis efficiency, and inhibits cardiolipin peroxidation-driven cytochrome c release.

Research Areas

Mitochondrial dysfunction and bioenergeticsIschemia-reperfusion injuryHeart failure modelsNeurodegeneration researchSarcopenia and muscle aging

SS-31 Dosages in Research

10mg50mg vials

Clinical trials used intravenous and subcutaneous dosing in the milligram-per-day range; animal studies typically use 1-5 mg/kg. Research-context only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C desiccated, protected from light. Reconstituted: 2-8C, use within 2-3 weeks.

SS-31 Supplier Price Comparison

SupplierProductPriceScore
Peptides, Steroid Powders & Biochemical Raw Materials SS-31 20mg Mitochondrial Protection Peptide 20mg — ★ 1.8
Peptide Manufacturer & Supplier SS-31 50MG 50mg — ★ 1.8
AEGÍS Peptides SS-31 — ★ 1.7
Leading Peptide Research Company SS-31 10mg 10mg — ★ 2.2
Cartman Gear LOBSTER SS-31 10MG KIT 10mg $1.20 ★ 1.8
AvaKlow Labs AKL SS-31 $19.99 ★ 1.7
Pure Peptides UK SS-31 10mg 10mg $24.99 ★ 2.7
HUK Aesthetics SS-31 10mg 10mg $25.00 ★ 3.2
Research SS-31 $26.50 ★ 1.6
Research Peptides UK Adonis SS31 – Research Peptide (RUO) $29.99 ★ 2.0
Buy Research Peptides UK SS-31 / Elamipretide – 10mg | Research-Grade Peptide 10mg $31.99 ★ 1.6
Home SS-31 10mg 10mg $32.00 ★ 2.1
Research Peptides & Laboratory Supplies UK SS-31 10mg 10mg $33.00 ★ 1.9
Home SS-31 $35.00 ★ 1.5
Glow Bougie SS-31 50mg Vial 50mg $39.00 ★ 2.5
Affordable Peptides Online SS-31 (Elamipretide) $39.00 ★ 1.7
Age Verification SS-31 10MG 10mg $40.00 ★ 1.7
AVERLA RESEARCH SS-31 $44.50 ★ 1.6
Buy Research Peptides Online — 99% Purity, COA SS-31 10mg 10mg $45.00 ★ 2.2
Green Lux Aminos Ss-31 10mg 10mg $45.00 ★ 1.6
Wholesale Medical Supplies for Clinics & Practitioners SS-31 $45.00 ★ 2.8
AVGSciences – US Medicine SS-31 10mg 10mg $45.95 ★ 3.2
Research Use Only Disclaimer SS-31 10mg 10mg $45.99 ★ 1.9
One moment, please... SS-31 $48.00 ★ 1.6
Buy Research Peptides Online SS-31 10MG 10MG $48.00 ★ 2.0
Elevate Core Peptides – Peptides for Sales Online – USA Made SS-31 10mg (Elamipretide) Research Peptide 10mg $50.00 ★ 1.6
Research Peptides & Laboratory Materials SS-31 (Elamipretide) 10mg 10mg $50.00 ★ 1.5
One moment, please... SS-31 (Elamipretide) $50.00 ★ 1.6
High SS-31 Canada – Research Peptide $50.00 ★ 1.8
Premium Lab SS-31 10 10mg $51.99 ★ 1.6
24Peptides SS-31 (Elamipretide) 10mg 10mg $54.00 ★ 2.2
One moment, please... SS-31 $59.00 ★ 1.7
Astra Labs SS-31 50mg 50mg $59.99 ★ 1.6
Buy Peptides for Laboratory Research SS-31 10mg 10mg $59.99 ★ 2.8
Alera Research SS31 (Elamipretide) – 10mg 10mg $59.99 ★ 1.7
Ambush Peptides SS-31 – 10mg 10mg $60.00 ★ 2.6
Medically Enhanced Rx SS-31 (10mg) 10mg $60.00 ★ 2.2
My account – Atlas Peptide Co. SS-31 (10 mg) 10mg $60.00 ★ 1.5
Adria Science SS-31 $60.50 ★ 1.8
Home SS-31 Peptide $63.99 ★ 1.7
Advanced Peptide Research SS-31 $64.99 ★ 1.9
Alpha Amino Labs SS-31 $65.00 ★ 1.9
Home SS-31 10MG 10MG $65.00 ★ 1.7
Aura Peptides USA SS-31 10mg 10mg $65.00 ★ 2.0
Home SS-31 10mg 10mg $65.00 ★ 2.0
808 Peptides LLC SS-31 $68.00 ★ 1.9
Australian Peptide Hub SS-31 $69.00 ★ 1.6
Fatburner online kaufen im Onlineshop von Fatburners.at Swiss Pharmaceuticals SS-31 $69.90 ★ 3.2
Black Helix Labs SS-31 (10mg) 10mg $70.00 ★ 1.6
American Peptide Innovations SS-31 $70.00 ★ 1.9

SS-31 FAQ

Rather than scavenging ROS after they form, SS-31 binds cardiolipin in the inner mitochondrial membrane and reduces ROS generation at the electron transport chain source, while improving ATP production efficiency.
Yes - as elamipretide it has completed multiple Phase 2/3 trials in primary mitochondrial myopathy, heart failure and Barth syndrome, making it one of the most clinically studied research peptides.
98%+ HPLC purity and mass spec identity at 639.8 Da. Note the sequence contains D-arginine and dimethyltyrosine - non-standard residues that cheap synthesis can get wrong.
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